Insulin-like growth factor-binding protein complex acid labile subunit, ALS, IGFALS, ALS
IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this protein are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP7478c was selected from the Center region of human IGFALS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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