Growth/differentiation factor 6, GDF-6, Bone morphogenetic protein 13, BMP-13, Growth/differentiation factor 16, GDF6, BMP13, GDF16
GDF6 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this protein result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP7483b was selected from the C-term region of human GDF6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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