IGF1 alpha Antibody (C-term) Blocking peptide

Product Overview

• Article Name: IGF1 alpha Antibody (C-term) Blocking peptide
• Biozol Catalog Number: ABT-BP7827B
• Supplier Catalog Number: BP7827b
• Alternative Catalog Number: ABT-BP7827B-500UG
• Manufacturer: Abcepta
• Category: Proteine/Peptide
• Alternative Names: Insulin-like growth factor I, IGF-I, Mechano growth factor, MGF, Somatomedin-C, IGF1, IBP1

Product Description

The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH, MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed sulfation factor, which later became known as somatomedin (Daughaday et al., 1972 [PubMed 4550398]). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2, MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986 [PubMed 3455760], Rosenfeld, 2003 [PubMed 14657423]).[supplied by OMIM]

Product Properties

• NCBI: 3479
• UniProt: P05019
• Form: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
• Target: The synthetic peptide sequence used to generate the antibody AP7827b was selected from the C-term region of human IGF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.