Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGKE shows specificity for arachidonyl-containing diacylglycerol. DGKE is expressed predominantly in testis.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP8125b was selected from the C-term region of human DGKE . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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