Tumor necrosis factor receptor superfamily member 13B, Transmembrane activator and CAML interactor, CD267, TNFRSF13B, TACI
TNFRSF13B is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1,and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP8557a was selected from the N-term region of human TNFRSF13B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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