GSDMB is a protein with 3 exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP8559c was selected from the Center region of human GSDMB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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