ATP-dependent RNA helicase DDX50, DEAD box protein 50, Gu-beta, Nucleolar protein Gu2, DDX50
DDX50 belongs to the RNA helicase family of proteins involved in unwinding double-stranded RNA during transcription and pre-mRNA splicing, ribosomal RNA synthesis, translation, RNA transport, and RNA stability and degradation. RNA helicases have an Asp-Glu-Ala-Asp (DEAD) motif within the catalytic domain, which gives the family its name (Valdez et al., 2002).
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP8763a was selected from the N-term region of human DDX50. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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