DYNC1I1 is the intermediate chains seem to help dynein bind to dynactin 150 kDa component. This protein may play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP9232b was selected from the C-term region of human DYNC1I1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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