Mitochondrial uncoupling protein 4, UCP 4, Solute carrier family 25 member 27, SLC25A27, UCP4
SLC25A27 is members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP9260c was selected from the Center region of human SLC25A27. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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