EF-hand domain-containing protein D2, Swiprosin-1, EFHD2, SWS1
EFHD2 may regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch. This protein controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Target:
The synthetic peptide sequence used to generate the antibody AP9285b was selected from the C-term region of human EFHD2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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