Homeobox protein Hox-C11, Homeobox protein Hox-3H, HOXC11, HOX3H
The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. HOXC11 binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development.