DCTN1 Antibody (N-term) Blocking Peptide

Catalog Number: ABT-BP9706A
Article Name: DCTN1 Antibody (N-term) Blocking Peptide
Biozol Catalog Number: ABT-BP9706A
Supplier Catalog Number: BP9706a
Alternative Catalog Number: ABT-BP9706A-500UG
Manufacturer: Abcepta
Category: Proteine/Peptide
Alternative Names: Dynactin subunit 1, 150 kDa dynein-associated polypeptide, DAP-150, DP-150, p135, p150-glued, DCTN1
DCTN1 is the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus.
NCBI: 1639
UniProt: Q14203
Form: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.