SARS-CoV-2 ORF3a Peptide (EPIYDEPTTTTSVPL)

Product Overview

• Article Name: SARS-CoV-2 ORF3a Peptide (EPIYDEPTTTTSVPL)
• Biozol Catalog Number: ABT-VGP1154
• Supplier Catalog Number: VGP1154
• Alternative Catalog Number: ABT-VGP1154-100UG
• Manufacturer: Abcepta
• Category: Proteine/Peptide
• Alternative Names: Accessory protein 3a, ORF3a protein, Protein 3a, Protein U274, Protein X16, sars-cov-2

Product Description

SARS-CoV-2 infection induces a storm of cytokines in laer stages of progression. The viral protein ORF3a activates the NLRP3 inflammasome via promotion of TNF receptor-associated factor 3 (TRAF3)-mediated ubiquitination of apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC). ORF3a protein activates pro-IL-1beta gene transcription and protein maturation, two signal essential to activation of the NLRP3 inflammasome.

Product Properties

• NCBI: 43740569
• UniProt: P0DTC3
• Form: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.