1400W dihydrochloride is a potent and selective inhibitor of human inducible NO synthase with Ki values of 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex.
Molecular Weight:
250.17
Purity:
99.60%
CAS Number:
[214358-33-5]
Formula:
C10H15N3.2HCl
Target:
NO Synthase
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