Gramicidin S is a cyclic peptide antibiotic produced by Bacillus brevis var. Gause-Brazhnikova. Gramicidin S exerts antibacterial activity by destroying membrane integrity and interfering with membrane protein function. Gramicidin S also inhibits ion channels, with IC50s of 41 µM, 24 µM, and 3 µM for Na+/K+-ATPase, tobacco leaf plasma membrane Mg2+/K+-ATPase, and rat heart plasma membrane Ca2+-ATPase, respectively.
Molecular Weight:
1141.45
Purity:
>99.0%
CAS Number:
[113-73-5]
Formula:
C60H92N12O10
Target:
Peptides
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