QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 humoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with subsequent release of caspase-1 dependent cytokines, IL-1beta and IL-18.
Molecular Weight:
1990.13
Purity:
99.87%
CAS Number:
[141256-04-4]
Formula:
C92H148O46
Target:
Adjuvants
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