Ac-FLTD-CMK is a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 µM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3.
Molecular Weight:
569.05
Purity:
>99.0%
CAS Number:
[2376255-48-8]
Formula:
C26H37ClN4O8
Target:
Caspase
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