Alrizomadlin (APG-115) is an oral active small molecule MDM2 protein inhibitor that binds to MDM2 protein.IC50 value and Ki The values are 3.8 nM and 1 nM, respectively. Alrizomadlin blocks MDM2 interaction with p53 and induces cell cycle arrest and apoptosis in a p53-dependent manner.
Molecular Weight:
642.59
Purity:
>98.5%, ee.: 100%
CAS Number:
[1818393-16-6]
Formula:
C34H38Cl2FN3O4
Target:
Mdm2
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