Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibits 2 µM Yoda1-induced Ca2+Incoming, IC50 values in HEK 293 cells and HUVECs are 1.3 µM and 1.5 µM, respectively.
Molecular Weight:
326.2
Purity:
99.95%
CAS Number:
[2253744-54-4]
Formula:
C13H9Cl2N3OS
Target:
Piezo Channel
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