RGB-286638 is a potent CDK inhibitor that inhibits cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 activity,IC50 1, 2, 3, 4, 5 and 5 nM, respectively, and can inhibit GSK-3beta, TAK1, Jak2 and MEK1.IC50 The values are 3, 5, 50, and 54 nM, respectively.
Molecular Weight:
618.55458
Purity:
>98.0%
CAS Number:
[784210-87-3]
Formula:
C29H37Cl2N7O4
Target:
CDK
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