Deoxyshikonin was isolated from comfrey Lithospermum erythrorhizon with antitumor activity. Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNAs in HMVEC-dLy, promotes the interaction of HIF-1alpha and HIF-1beta subunits, and binds to HIF-specific DNA sequences.
Molecular Weight:
272.3
Purity:
>99.0%
CAS Number:
[43043-74-9]
Formula:
C16H16O4
Target:
HIF
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