WEHI-9625 is a first-in-class tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX.
Molecular Weight:
593.71
Purity:
>99%
CAS Number:
[2595314-46-6]
Formula:
C34H27NO5S2
Target:
VDAC
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