E6446 is an inhibitor of Toll-like receptor (TLR) 7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interactions in vitro. E6446 is also a potent SCD1 inhibitor (KD: 4.61 µM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling.
Molecular Weight:
449.59
Purity:
>98.0%
CAS Number:
[1219925-73-1]
Formula:
C27H35N3O3
Target:
TLR
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