Inavolisib, CAS [[2060571-02-8]]

Product Overview

• Article Name: Inavolisib, CAS [[2060571-02-8]]
• Biozol Catalog Number: AMO-M11405
• Supplier Catalog Number: M11405
• Alternative Catalog Number: AMO-M11405-1MG,AMO-M11405-5MG,AMO-M11405-10MG,AMO-M11405-25MG,AMO-M11405-50MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: GDC-0077, RG6114,RO-7113755

Product Description

Inavolisib (GDC-0077, RG6114) is a potential best-in-class, orally selective PI3Kalpha inhibitor (IC50=0.038 nM). GDC-0077 (RG6114) exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. GDC-0077 (RG6114) is more selective for mutants compared to wild-type PI3Kalpha. It can trigger the degradation of mutation-producing PIK3alpha.

Product Properties

• Molecular Weight: 407.37
• Purity: >99%
• CAS Number: [2060571-02-8]
• Formula: C18H19F2N5O4
• Target: PI3K