Divarasib (GDC-6036) is an orally active, selective, covalently mutated KRAS G12C inhibitor with an IC50<0.01 µM for K-Ras G12C. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylated HCC1171 cells. can be used in studies related to non-small cell lung cancer ( NSCLC) related studies.
Molecular Weight:
622.06
Purity:
>99.0%
CAS Number:
[2417987-45-0]
Formula:
C29H32ClF4N7O2
Target:
Ras
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