TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin
Recombinant human TNF-alpha protein (E. coli) is a homotrimer with a subunit molecular mass of 17.3 kDa. TNF-a plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases, and in viral, bacterial, fungal, and parasitic infections. ED50 < 30.0 pg/ml, measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D, corresponding to a specific activity of > 3.3 * 107 units/mg.
Purity:
>98%, Endotoxin < 0.2 EU/µg
CAS Number:
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Target:
Cytokines and Growth Factors
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