RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively, also inhibits GSK-3beta, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM.
Molecular Weight:
545.63
Purity:
>98.0%
CAS Number:
[784210-88-4]
Target:
CDK
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