Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively.
Molecular Weight:
546.19
Purity:
99.77%
CAS Number:
[1103522-45-7]
Formula:
C16H14Br2N6O4S
Target:
Endothelin Receptor
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