GDC-0623, CAS [[1168091-68-6]]

Product Overview

• Article Name: GDC-0623, CAS [[1168091-68-6]]
• Biozol Catalog Number: AMO-M14169
• Supplier Catalog Number: M14169
• Alternative Catalog Number: AMO-M14169-5MG,AMO-M14169-10MG,AMO-M14169-50MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: RG 7421, MEK inhibitor 1

Product Description

GDC-0623 (RG 7421) is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC50=42 nM) versus A375 (BRAFV600E, EC50=7 nM).

Product Properties

• Molecular Weight: 456.21
• Purity: >99%
• CAS Number: [1168091-68-6]
• Target: MEK