GW806742X hydrochloride is an ATP mimetic and potent inhibitor of MLKL and necroptosis, slowing down MLKL membrane translocation and binding to the MLKL pseudokinase domain with a Kd value of 9.3 µM. GW806742X hydrochloride has anti-VEGFR2 activity (IC50=2 nM). GW806742X hydrochloride has anti-VEGFR2 activity (IC50=2 nM).
Molecular Weight:
610.01
Purity:
>99%
CAS Number:
[579515-63-2 free base]
Formula:
C25H23ClF3N7O4S
Target:
Necroptosis
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