Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin binds some BMPs such as BMP4 with high affinity and others such as BMP7 with lower affinity. It antagonizes BMP bioactivities by blocking epitopes on BMPs that are needed for binding to both type I and type II receptors. Accession : P97466.
Purity:
>95%, Endotoxin < 1 EU/ug
CAS Number:
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Target:
Cytokines and Growth Factors
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