Gefitinib (ZD1839) is an EGFR tyrosine kinase and Akt phosphorylation inhibitor. Gefitinib significantly down-regulates CD47 expression and increases DC phagocytosis in non-small cell lung cancer cells such as PC9, H1437 and H1573. Gefitinib combined with CD47 antibody can enhance the phagocytosis of macrophages.
Molecular Weight:
446.90
Purity:
99.97%
CAS Number:
[184475-35-2]
Formula:
C22H24ClFN4O3
Target:
EGFR/HER2
* VAT and and shipping costs not included. Errors and price changes excepted
