Vemurafenib (PLX4032) is a first-in-class, potent, selective inhibitor of B-Raf that inhibits RAFV600E and C-RAF-1 activity with IC50s of 31 nM and 48 nM, respectively.In addition, Vemurafenib induces autophagy.
Molecular Weight:
489.92
Purity:
>99.5%
CAS Number:
[918504-65-1]
Formula:
C23H18ClF2N3O3S
Target:
Raf
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