Ruxolitinib (INCB018424) is a first-in-class, potent, selective JAK1/2 inhibitor with an IC50 of 3.3 nM/2.8 nM. It is more than 130-fold more selective for JAK1, JAK2, and JAK3 than JAK3. It can be used in studies related to pemphigus, myelofibrosis and vitiligo.
Molecular Weight:
306.37
Purity:
99.93%
CAS Number:
[941678-49-5]
Formula:
C17H18N6
Target:
JAK
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