Gamma-Mangostin (gamma-Mangostin) is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 µM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities.
Molecular Weight:
396.43
Purity:
>99.0%
CAS Number:
[31271-07-5]
Formula:
C23H24O6
Target:
COX
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