KU-55933 is a cell-permeable ATP-competitive inhibitor of ATM (IC50 = 13 nM, Ki = 2.2 nM) with selectivity over other PIKK family kinases (IC50 = 2.5, 9.3, 16.6 µM for DNAPK, mTOR, PI 3-K, respectively, IC50 > 100 µM for PI 4-K and ATR).
Molecular Weight:
395.49
Purity:
>99.0%
CAS Number:
[587871-26-9]
Formula:
C21H17NO3S2
Target:
ATM/ATR
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