Ciclosporin A, CsA, Cyclosporin A, Antibiotic S 7481F1
Cyclosporine A (CsA,Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation.
Molecular Weight:
1202.61
Purity:
100.00%
CAS Number:
[59865-13-3]
Formula:
C62H111N11O12
Target:
Immunology/Inflammation
* VAT and and shipping costs not included. Errors and price changes excepted