Lonidamine (AF-1890) is a novel CFTR open channel blocker with an IC50 of 0.85 mM, which inhibits aerobic glycolysis in cancer cells. Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki=2.5 µM).
Molecular Weight:
321.16
Purity:
99.55%
CAS Number:
[50264-69-2]
Formula:
C15H10Cl2N2O2
Target:
CFTR
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