ASP3026 is a selective and oral active anaplastic lymphoma kinase (ALK) inhibitor with a IC50 value of 3.5 nM. ASP3026 can inhibit the phosphorylation of IGF-1R, STAT3, AKT and JNK proteins, and induce the cleavage of caspase 3 and PARP. It also inhibited ROS and ACK.
Molecular Weight:
580.76
Purity:
100.00%
CAS Number:
[1097917-15-1]
Formula:
C29H40N8O3S
Target:
ALK
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