2-methoxyestradiol (2-ME2), an endogenous metabolite of 17beta -estradiol (E2) with oral activity, is an apoptosis inducer and angiogenesis inhibitor with effective antitumor activity. Methoxyestradiol can also destabilize microtubules. Methoxyestradiol is a potent inhibitor of superoxide dismutase (SOD) and reactive oxygen species (ROS) that can induce autophagy in transformed cell line HEK293, cancer cell line U87 and HeLa.
Molecular Weight:
302.41
Purity:
>99.0%
CAS Number:
[362-07-2]
Formula:
C19H26O3
Target:
HIF
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