Semaxinib (SU5416) is a novel small molecule multi-targeted kinase inhibitor of VEGF receptors, c-kit and FLT3. Semaxinib reversibly inhibits ATP binding to the tyrosine kinase domain of VEGFR2, potentially inhibiting VEGF-stimulated endothelial cell migration and proliferation, thereby reducing tumor microvasculature.
Molecular Weight:
238.28
Purity:
99.81%
CAS Number:
[204005-46-9]
Formula:
C15H14N2O
Target:
VEGFR/PDGFR
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