WZ811 is a highly competitive CXCR4 antagonist with oral activity. WZ811 effectively inhibited CXCR4/SDF-1 (also known as CXCL12) -mediated regulation of cAMP level (EC50=1.2 nM) and SDF-1-induced matrix glue invasion (EC50=5.2 nM) in cells.
Molecular Weight:
290.36
Purity:
>99%
CAS Number:
[55778-02-4]
Formula:
C18H18N4
Target:
CXCR
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