MYCi361 is a MYC inhibitor that engages MYC inside cells, disrupts MYC/MAX dimers, and impairs MYC-driven gene expression. MYCi361 binds to MYC with Kd of 3.2 µM. MYCi361 suppresses in vivo tumor growth, increases tumor immune cell infiltration, upregulates PD-L1 on tumors, and sensitizes tumors to anti-PD1 immunotherapy.
Molecular Weight:
594.86
Purity:
>99%
CAS Number:
[2289690-31-7]
Formula:
C26H16ClF9N2O2
Target:
c-Myc
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