Lanraplenib (GS-9876, GS-SYK) is a potent, highly selective and orally active inhibitor of Spleen Tyrosine Kinase (SYK) with IC50 of 9.5 nM. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.
Molecular Weight:
443.5
Purity:
>99%
CAS Number:
[1800046-95-0]
Formula:
C23H25N9O
Target:
Syk
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