MLN2480 is an orally active, CNS-permeable, highly selective inhibitor of type II RAF kinase that inhibits both monomeric (class I mutant) and dimeric forms of RAF and does not cause aberrant activation of the MAPK pathway caused by type I RAF inhibitors. In addition, MLN2480 inhibits the growth of tumors harboring BRAF fusions or BRAF V600 mutations and can be used in studies related to gliomas.
Molecular Weight:
506.29
Purity:
>99.0%
CAS Number:
[1096708-71-2]
Formula:
C17H12Cl2F3N7O2S
Target:
Raf
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