GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1 protein and recruit the E3 ligase Von Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.
Molecular Weight:
861.93
Purity:
>98.5%
CAS Number:
[2490599-18-1]
Formula:
C43H46F3N7O7S
Target:
PROTAC
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