Alpelisib (Byl-719) is an effective, selective PI3Kalpha inhibitor with oral activity. Alpelisib (Byl-719) was targeted to PIK3CA mutated carcinoma. The IC50 of Alpelisib (Byl-719) against P110 alpha, P110 gamma, p110delta and P110 beta were 5 nM, 250 nM, 290 nM and 1200 nM, respectively. It has antitumor activity.
Molecular Weight:
441.47
Purity:
100.0%
CAS Number:
[1217486-61-7]
Formula:
C19H22F3N5O2S
Target:
PI3K
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