GA-017 is a potent and selective inhibitor of LATS1 and LATS2 (large tumor suppressor kinase 1/2) with IC50 values of 4.10 and 3.92 nM, respectively.GA-017 is a cell proliferation activator.GA-017 promotes YAP/TAZ activation and nuclear translocation.GA-017 promotes cell growth in 3D culture conditions.GA-017 Enhances the formation of mouse intestinal organoid isolates.
Molecular Weight:
343.38
Purity:
>98.5%
CAS Number:
[2351906-74-4]
Formula:
C18H21N3O4
Target:
YAP
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