Icenticaftor (QBW251) is an oral enhancer of the cystic fibrosis transmembrane conductance regulator (CFTR) channel with an EC50 of 79 nM for F508del and 497 nM for G551D CFTR. Icenticaftor can be used in chronic obstructive pulmonary disease (COPD) and cystic fibrosis studies.
Molecular Weight:
361.24
Purity:
>99%
CAS Number:
[1334546-77-8]
Formula:
C12H13F6N3O3
Target:
CFTR
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