BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 µM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 µM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration.
Molecular Weight:
418.7748096
Purity:
>99%
CAS Number:
[406191-34-2]
Formula:
C16H10ClF3N2O4S
Target:
Others
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